General Cell Lines and Cell Cultures
iQ Biosciences Purified Cynomolgus Monkey CD14+ Cells, 1M cells/vial
High-quality, high-viability (> 90%) CD14+ cells purified from cynomolgus macaque peripheral blood mononuclear cells (PBMC) by magnetic isolation. Highly enriched (typically > 80%) post-selection purity achieved via magnetic isolation. Ideal source for cynomolgus monocytes and neutrophils. Used for a wide variety of safety assessment and functional assays. All orders come with an iQ Certificate of Analysis.The following donor requests can be accommodated if inventory is available: - Single or multiple donors for a particular product (SKU). Indicate number of vials from each individual donor - Donor-matched PBMCs
Eurofins Discoverx PathHunter U2OS FGFR1-α-Klotho Functional Assay, 2 vials. (93-1117C3)
The PathHunter U2OS FGFR1-α-Klotho Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated FGFR1 and α-Klotho dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged FGFR1 and an EA-tagged SH2 domain protein. It also overexpresses an untagged coreceptor, α-Klotho. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Eurofins Discoverx PathHunter CHO-K1 rVIPR1 β-Arrestin Cell Line, 2 vials. (93-0913C2)
The PathHunter rVIPR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. VIP) based activation of rVIPR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rVIPR1 and EA-tagged β-Arrestin-2. Activation of rVIPR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Genscript Corporation CHO-K1/MRGPRX2 Stable Cell Lin
Recombinant CHO-K1 cells stably overexpress human mas-related G-protein coupled receptor member X2 (MRGPRX2) on the surface and contain high levels of G protein G q and G i to couple with the receptor in downstream signaling pathways
Amsbio LLC Human Peripheral Blood Mononuclear Cells (PBMCs)| Cryopreserved| (POOLED) 15 million cells/vial
Human Peripheral Blood Mononuclear Cells (PBMCs) Cryopreserved (POOLED) 15 million cells/vial
Eurofins Discoverx U2OS GRM5 Gq Cell Line, 2 vials. (95-1020C3)
The GRM5 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. L-glutamate) based activation of GRM5 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GRM5, a naturally Gq coupled GPCR. Upon activation of GRM5, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Haemophilus influenzae; type b
Haemophilus influenzae strain ES2593 [Eagan mutant] is a whole-genome sequenced bacterial strain with applications in respiratory disease research. This strain has genotype ES hktE7::mini-Tn10Cm and is typed as serotype b.
ATCC Prevotella pallens
Prevotella pallens strain NCTC 13042 is a bacterial type strain that was isolated from the saliva of a human child. This strain is propagated anaerobically on modified chopped meat medium and trypticase soy medium.
ATCC Rhizobium leguminosarum
Rhizobium leguminosarum strain 3D1k2 is a whole-genome sequenced bacterium that was isolated from Arlington Farm in Virginia.
ATCC Influenza A virus (H1N1); A/New Jersey/8/76
Influenza A virus (H1N1) strain A/New Jersey/8/76 (Hsw N1) is propagated in SPF chicken embryonated eggs. This strain was isolated in 1976 during an outbreak of respiratory disease at Fort Dix in New Jersey. This product is whole-genome sequenced and has applications in influenza research.
ATCC Escherichia coli; BL21
Escherichia coli strain BL21 is a whole-genome sequenced bacterium that can be used as a host for bacteriophages T3 (ATCC BAA-1025-B1) and T7 (ATCC BAA-1025-B2).
World Precision Instrument AutoLCI Adapter for 90/100mm Dish-Single
With EVOM™ AutoLCI, cells cultured in different vessel types can be imaged. Interchangeable vessel adapters can accommodate various vessel types including well-plate, culture flask, and culture dish. The system includes a well-plate adapter, but you can buy separately different adapters for a variety of vessels used.
ATCC Sclerotinia sclerotiorum; Ss-3
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
ATCC Burkholderia cepacia
This strain of Burkholderia cepacia has applications in opportunistic pathogen and respiratory disease research.